Thermo Fisher Scientific LOXL2 Monoclonal Antibody (262418)
인간 LOXL2 단백질을 인식하는 마우스 단클론 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 단백질 A/G로 정제된 비결합형 형태입니다. PBS와 trehalose로 안정화되어 있으며, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 262418 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Lysyl Oxidase Homolog 2 (LOXL2) Gln26–Gln744 (predicted) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576362 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin.
A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.
The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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