Thermo Fisher Scientific DLL3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Target Information

Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway and inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in the DLL3 gene lead to truncal shortening relative to limbs, abdominal protrusion, abnormal spinal curvature, and occasionally a plagiocephaly-torticollis sequence.
DLL3 may be required to divert neurons along a specific differentiation pathway.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.