Thermo Fisher Scientific DLL3 Polyclonal Antibody
DLL3 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 인간과 마우스 반응성. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태로 연구용에 최적화.
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- BS-7860R
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human DLL3 (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway and inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in the DLL3 gene lead to truncal shortening relative to limbs, abdominal protrusion, abnormal spinal curvature, and occasionally a plagiocephaly-torticollis sequence.
DLL3 may be required to divert neurons along a specific differentiation pathway.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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