Thermo Fisher Scientific Cardiac Troponin T Monoclonal Antibody (1A11)
심근 트로포닌 T 단백질을 인식하는 마우스 단일클론 항체로 다양한 종에서 반응. Western blot, ELISA, Affinity Purification에 사용 가능. 단백질 A로 정제된 액상 형태, 4°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Cardiac Troponin T Monoclonal Antibody (1A11)
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| ELISA | - | View 1 publication |
| Affinity Purification (AP) | Assay-dependent | View publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Cat, Fish, Goat, Human, Mouse, Pig, Rabbit, Rat |
| Published Species | Rat, Rodent |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A11 |
| Immunogen | Full length human cardiac Troponin T protein (UniProt ID: P45379-1, range 1–298, length 298) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.8 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_795631 |
Product Specific Information
MA1-24611 detects cardiac Troponin T from mouse, rat, bovine, feline, canine, fish, goat, porcine, rabbit, and human samples.
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium concentration changes and is essential for proper muscle function and myofibril formation.
In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Expression levels are affected by heart failure. Mutations in Cardiac Troponin T are associated with familial hypertrophic cardiomyopathy and dilated cardiomyopathy. The gene undergoes alternative splicing, producing multiple tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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