Thermo Fisher Scientific CD266 (TWEAK Receptor) Recombinant Rabbit Monoclonal Antibody (SN20-07)
CD266(TWEAK Receptor)에 특이적인 재조합 토끼 단일클론 항체로, 높은 특이성과 일관된 로트 간 재현성을 제공. Western blot 및 IHC(P) 적용 가능. HEK293 세포 발현 시스템을 사용하며, 단백질 A로 정제된 1 mg/mL 액상 형태. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN20-07 |
| Immunogen | Synthetic peptide within Human TWEAKR aa 80–129 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809620 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
TWEAK is a member of the TNF family and was initially described as a weak inducer of apoptosis. A receptor for TWEAK, known as TweakR, was identified via expression cloning from a HUVEC cell cDNA library.
TweakR belongs to the TNF receptor superfamily and can initiate proliferative signaling by binding to TRAF1, TRAF2, and TRAF3. TweakR mRNA is upregulated during tissue regeneration in the aorta and liver and may play roles in vascular cell migration and angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-32339_CD266_Q9NP84-1_Rabbit.svg, MA5-32339_CD266_Q9NP84-1_Rabbit_PDP.jpeg)
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