Thermo Fisher Scientific Factor 7 Polyclonal Antibody
사람 유래 Factor VII를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. KLH 결합 합성 펩타이드(aa 301-400)로 면역화. Protein A로 정제된 액상 형태이며, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Factor VII heavy chain (amino acids 301–400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. It circulates in the blood as a zymogen and is activated by factor IXa, factor Xa, factor XIIa, or thrombin. Upon activation, it forms a heavy chain (catalytic domain) and a light chain (two EGF-like domains) linked by a disulfide bond. In the presence of factor III and calcium ions, activated factor VII promotes the coagulation cascade by converting factor IX to IXa and/or factor X to Xa. Defects in F7 production can lead to coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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