Thermo Fisher Scientific CD15 Monoclonal Antibody (ABM119)
인간 CD15 항원을 인식하는 Mouse IgM 단클론 항체로, IHC(P)에서 2–10 µg/mL로 사용 가능. 골수 양성 대조군으로 적합하며, 세포막 및 세포질 염색에 유용. 0.5 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ABM119 |
| Immunogen | Human myelomonocytic leukemia cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Bone Marrow
- Cellular location: Cytoplasm, membrane
Target Information
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisaccharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of various cell types such as granulocytes, mast cells, monocytes, macrophages, gastric mucosa cells, nervous system cells, and various tumor cells.
Variants include sialyl-Lewis x and sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation based on calcium-dependent Le(x)-Le(x) interaction, involved in embryo compaction and teratocarcinoma cell autoaggregation.
Sialyl-Le(x) and sialyl-Le(a) are ligands of selectins. CD15 expression is widely used to confirm diagnosis of Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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