Thermo Fisher Scientific NMDAR2A Monoclonal Antibody (N327A/38), PE
PE 형광 표지된 NMDAR2A 단클론 항체로 인간, 마우스, 랫트 시료에 반응. WB, IHC, ICC 등 다양한 응용 가능. 단백질 G 정제, 보존제 없음, 4°C 보관. GluN2A/NR2A 검출에 특이적이며 NR2B 비반응.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N327A/38 |
| Immunogen | Fusion protein amino acids 75–325 (extracellular N-terminus) of rat GluN2A/NR2A |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932068 |
Additional Formats
Product Specific Information
- 1 µg/mL of MA5-45614 was sufficient for detection of GluN2A/NR2A in 20 µg of COS cells transiently transfected with GFP-tagged NR2A lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 170 kDa.
- Does not react with NR2B.
- This antibody was formerly sold as clone S327A-38.
Target Information
N-methyl-D-aspartate (NMDA) receptors are ionotropic glutamate-gated ion channels involved in long-term potentiation, a mechanism underlying memory and learning. NMDA receptor channels are heteromers composed of the essential subunit NMDAR1 (GRIN1) and one or more of the NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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