Thermo Fisher Scientific LEF1 Monoclonal Antibody (3A12)
LEF1 단백질을 인식하는 마우스 단클론 항체로, Western blot 등 연구용에 적합합니다. 합성 펩타이드(236–242 aa)를 면역원으로 제작되었으며, PBS 버퍼에 0.08% sodium azide가 포함된 액상 형태입니다. -20°C에서 보관하며, 동결·해동 반복은 피해야 합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A12 |
| Immunogen | Synthetic peptide corresponding to residues 236–242 of human LEF-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076472 |
Target Information
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The encoded protein binds to a functionally important site in the T-cell receptor-alpha enhancer, conferring maximal enhancer activity. It is involved in the Wnt signaling pathway and may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors and have been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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