Thermo Fisher Scientific SNAP alpha Monoclonal Antibody (4E4)
Thermo Fisher Scientific의 SNAP alpha Monoclonal Antibody (4E4)는 인간 a-SNAP 단백질을 인식하는 마우스 IgG1 단일클론 항체입니다. Western blot과 면역침강(IP) 실험에 적합하며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000
- References: -
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
- References: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E4 |
| Immunogen | Human a-SNAP protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2150853 |
Product Specific Information
A suggested positive control for this product is rat brain lysate.
Target Information
SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF), are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion, and transcytotic vesicles-to-plasma membrane transport.
Vesicle-to-target membrane docking occurs when the vesicle SNARE binds to its cognate target membrane SNARE. α-SNAP (or β-SNAP in brain) then binds to this docking complex and mediates the binding of NSF, forming a 20S fusion particle. Once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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