PBS Biotech Mini Vertical-Wheel Bioreactor

PBS-Mini Vertical-Wheel Bioreactor

Jump start your cell therapy process

Experience the benefits of Vertical-Wheel mixing in a scale-down model. Cell culture processes optimized using the PBS-0.1 Mini and PBS-0.5 Mini can be confidently scaled up into larger scale Vertical-Wheel bioreactors.

Highlights:

• Universal base unit is compatible with either size of single-use vessels (0.1L or 0.5L working volumes)
• Designed for use in incubator for temperature and gas control
• Removable caps on single-use vessels allow for sterile liquid handling in biosafety hood
• Product contact materials meet regulatory requirements for first-in-human clinical trials

Technical Specifications:

Case Studies

Defined Biomatrices Accelerate MSC Manufacturing Across Scales

T Cell Expansion in PBS-Mini Using CellGenix Reagents

Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors

Transcriptome Profiling of Human Pluripotent Stem Cell-Derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions

Initial Power Measurements for a Family of Novel Bioreactors

Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing

User Resources

PBS-Mini User Manual

PBS-Mini Datasheet

FAQ

How can I monitor process parameters during a cell culture run?

The 3L bioreactor’s software allows for customizable programming of process
controls and real-time monitoring of parameters using various sensors.
Feedback loops can be used to pause a run based on deviations from a set range.

What are recommended methods for sampling and harvesting?

Both sampling and harvesting of cells can be achieved by unscrewing the orange cap
on top of the single-use vessel (one cap on 0.1L, two caps on 0.5L vessel) and using
a pipette to withdraw media. It is recommended to perform these procedures under
a biosafety hood.

What is the function of the power accessory cable?

This accessory allows the power cables from four different Mini bases
to be combined into one plug for a wall outlet.

I have other questions regarding usage or troubleshooting of the PBS Mini.

Please use the Products and/or Service quote form to submit any questions or
inquiries related to a specific product(s).

What data are available demonstrating the performance of Vertical-Wheel bioreactors?

Our Publications section lists numerous examples of cell culture performance data
for various cell types generated by customers and collaborators as well as by
our BioLab team.