Thermo Fisher Scientific FAM3B Polyclonal Antibody
FAM3B 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 사용 가능하며, 사람·마우스·랫트 반응성. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific FAM3B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FAM3B (Accession P58499), corresponding to amino acid residues S187–S235 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851753 |
Product Specific Information
Antibody detects endogenous levels of total FAM3B.
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures.
It is highly expressed in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine.
FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity.
Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species.
Three isoforms of FAM3B (A, B, and C) exist due to alternative splicing events.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-102346_FAM3B_P58499-1_Rabbit.svg)
(이미지: PA5-102346_FAM3B_P58499-1_Rabbit_PDP.jpeg)
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