Thermo Fisher Scientific TARBP2 Monoclonal Antibody (OTI7C1), TrueMAB
TARBP2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P)에서 검증됨. 인간, 생쥐, 랫트 반응성. 무보존제, 동결건조 형태로 제공되며 1 mg/mL 농도. 연구용으로 HIV-TAR RNA 결합 및 miRNA 처리 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7C1 |
| Immunogen | Full length human recombinant protein of human TARBP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TRBP (TARBP2) is a dsRNA-binding protein containing two conserved dsRNA-binding domains and a C-terminal basic region.
It binds HIV-TAR RNA and enhances HIV-1 long terminal repeat expression, while inhibiting host antiviral mechanisms via PKR interaction.
TRBP associates with Ago2 and is an integral component of the Dicer-containing complex, playing a key role in microRNA processing and RISC assembly.
It is also involved in cellular growth and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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