Thermo Fisher Scientific TP73 Monoclonal Antibody (OTI3C5), TrueMAB
TP73 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 IHC(P) 검증 완료. Human 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 연구용으로 DNA 손상 관련 세포사멸 연구에 적합.
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Thermo Fisher Scientific TP73 Monoclonal Antibody (OTI3C5), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 167–409 of human TP73 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882
Target Information
TP73 (p73) participates in the apoptotic response to DNA damage.
Isoforms containing the transactivation domain are pro-apoptotic, while isoforms lacking the domain are anti-apoptotic, blocking the function of p53 and transactivating p73 isoforms.
May function as a tumor suppressor protein.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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