Thermo Fisher Scientific IFITM3 Polyclonal Antibody, MaxPab
IFITM3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며 인간 및 생쥐 시료에 반응. PBS 용액 형태로 보존제가 없으며, 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IFITM3 (AAH06794, 1–133 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MNHTVQTFFS PVNSGQPPNY EMLKEEHEVA VLGAPHNPAP PTSTVIHIRS ETSVPDHVVW SLFNTLFMNP CCLGFIAFAY SVKSRDRKMV GDVTGAQAYA STAKCLNIWA LILGILMTIL LIVIPVLIFQ AYG
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family.
These proteins are induced by type I and II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoter regions.
IFITM proteins are involved in cellular anti-proliferative activity and homotypic cell adhesion functions, and are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis.
IFITM3 is a 133 amino acid membrane protein induced by IFN-α and IFN-γ, and its expression can be regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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