Thermo Fisher Scientific IFITM3 Polyclonal Antibody, MaxPab
IFITM3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료 반응성이 있으며, 액상 형태로 제공되고 PBS buffer에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IFITM3 (NP_066362.1, 1–133 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSHTVQTFFS PVNSGQPPNY EMLKEEHEVA VLGGPHNPAP PTSTVIHIRS ETSVPDHVVW SLFNTLFMNP CCLGFIAFAY SVKSRDRKMV GDVTGAQAYA STAKCLNIWA LILGILMTIL LIVIPVLIFQ AYG
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family. These proteins are induced by type I and II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoter regions. IFITM proteins are involved in cellular anti-proliferative activities and homotypic cell adhesion functions of interferons.
IFITM3 is a 133 amino acid protein induced by IFN-alpha and IFN-gamma, and its expression can be regulated by TEF-1, Brg-1, and Sp1. IFITM genes are often upregulated in various cancer cells, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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