Thermo Fisher Scientific BAD Polyclonal Antibody
인간 BAD 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500–1:2,000 희석 비율로 사용 가능. 보존제 무첨가로 고순도 Protein A 및 항원 친화 크로마토그래피 정제. 단기 4°C, 장기 -20°C 보관 권장. 세포사멸 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of Human BAD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787694 |
Product Specific Information
- This product is preservative free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human BAD.
Target Information
The protein encoded by BAD is a member of the BCL-2 family, which regulates programmed cell death.
This protein promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity.
Its proapoptotic activity is regulated by phosphorylation, involving kinases such as AKT and MAP kinase, and phosphatase calcineurin.
Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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