Thermo Fisher Scientific ABCC11 Monoclonal Antibody (7C12/4)

Thermo Fisher Scientific ABCC11 Monoclonal Antibody (7C12/4)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA1-40221 detects MRP-8 from human samples.
It has been successfully used in ELISA, flow cytometry, and Western blot applications.
The immunogen is the human MRP-8 epitope.

Target Information

ABCC11 is a member of the ATP-binding cassette (ABC) transporter superfamily.
ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
This ABC full transporter belongs to the MRP subfamily, which is involved in multi-drug resistance.
The gene product participates in processes involving bile acids, conjugated steroids, and cyclic nucleotides.
A SNP in this gene determines human earwax type.
ABCC11 and ABCC12 are derived by duplication and both localized to chromosome 16q12.1.
Multiple alternatively spliced transcript variants have been described for this gene.

Usage Notice

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.