Thermo Fisher Scientific Lactoferrin Monoclonal Antibody (265-1K1)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA1-40219 detects Lactoferrin from human samples.
It has been successfully used in ELISA, immunohistochemistry (frozen), and Western blot applications.
The immunogen is human lactoferrin.

Target Information

Lactoferrin (LF) is an iron-binding glycoprotein consisting of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺).
It is found in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules.

Lactoferrin exhibits diverse biological functions, including:

• Regulation of iron homeostasis
• Host defense against microbial infections
• Anti-inflammatory activity
• Regulation of cell growth and differentiation
• Protection against cancer development and metastasis

LTF acts as a first-line defense by binding Fe³⁺ and removing it from the environment, and also possesses bactericidal and proteolytic activities.
Three isoforms (LTF-α, LTF-β, LTF-γ) are known, and receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.