Thermo Fisher Scientific Phospho-Amyloid Precursor Protein (Ser730) Polyclonal Antibody
인간 APP Ser730 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, APP 관련 신경질환 연구에 활용 가능. Protein A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Amyloid Precursor Protein (Ser730) Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S730 of human APP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11004386 |
Product Specific Information
This antibody is predicted to react with mouse, porcine, non-human primate, and rat based on sequence homology.
Target Information
Amyloid Precursor Protein (APP), also known as Amyloid beta precursor protein, functions as a cell surface kinesin I membrane receptor mediating axonal transport of beta-secretase and presenilin 1. APP is crucial for neurite growth, neuronal adhesion, and axonogenesis. It is a 100–140 kDa transmembrane glycoprotein with several isoforms derived from alternative splicing. Proteolytic cleavage of APP by beta- and gamma-secretases generates beta amyloid, the main component of senile plaques, a hallmark of Alzheimer’s disease. Abnormal APP regulation is also implicated in Down’s syndrome, early-onset familial Alzheimer’s disease, and cerebral hemorrhage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.