Thermo Fisher Scientific CD36 Polyclonal Antibody, HRP
CD36 단백질을 인식하는 HRP 결합 폴리클로날 항체로 Western blot 및 IHC에 적합. 다양한 종에서 반응하며, 항원 친화 크로마토그래피로 정제됨. 4°C 암소 보관, 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide mapping to a region of human CD36 between residues 100–200 |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 0.90 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2550675 |
Product Specific Information
- Western blot shows a band at approximately 75–80 kDa.
- The difference between theoretical and observed molecular weight is likely due to heavy glycosylation and palmitoylation.
- Suggested positive control: antigen standard for CD36 (transient overexpression lysate).
Target Information
CD36, also known as scavenger receptor class B member 3, is a membrane protein expressed on macrophages, platelets, and adipocytes. It plays key roles in lipid metabolism, inflammation, and atherosclerosis, mediating recognition and uptake of oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 also functions as a receptor for thrombospondin and collagen, and mediates cytoadherence of Plasmodium falciparum-infected erythrocytes.
Mutations in this gene can cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants exist.
Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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