Thermo Fisher Scientific MUS81 Monoclonal Antibody (2G10/3)
MUS81 단백질을 검출하기 위한 Mouse monoclonal antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간 시료에서 검증됨. 액상 형태로 제공되며 2–8°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| Immunoprecipitation (IP) | 1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G10/3 |
| Immunogen | Human Mus81 from Sp2/0 Ag.14 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at −20°C. |
| Shipping conditions | Wet ice |
| RRID | AB_2147131 |
Product Specific Information
MA1-5837 detects Mus81 in human samples.
It has been successfully used in Western blot and immunoprecipitation procedures.
The immunogen is human Mus81.
Target Information
MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease that prefers branched DNA structures with a 5′-end at the branch nick.
Typical substrates include 3′-flap structures, replication forks, and nicked Holliday junctions.
It may be required in mitosis for the processing of stalled or collapsed replication forks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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