Thermo Fisher Scientific Lamin B1/B2 Monoclonal Antibody (X223)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

X223

Immunogen

Nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

10-15 µg/mL

Storage conditions

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Shipping conditions

Wet ice

RRID

AB_2139351

Product Specific Information

MA1-5822 detects Lamin B1 & B2 in human, bovine, and rat samples, and Lamin B2 in mouse.

MA1-5822 has been successfully used in immunofluorescence and Western blot procedures.

The MA1-5822 immunogen is nuclear pore complex-lamina fraction of XLKE-A6 cells.

Store at 4ºC of one month, or in small aliquots at -20ºC for longer periods, avoiding freeze/thaw cycles.

Target Information

This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.