Thermo Fisher Scientific GP6 Polyclonal Antibody
Rabbit polyclonal antibody against human GP6 for WB and ELISA applications. Detects cell membrane protein involved in platelet activation. Supplied as liquid, affinity purified, 1.61 mg/mL in PBS with glycerol. For research use only.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GP6 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 21–267 of human GP6 (NP_0574475) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.61 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805948 |
Product Specific Information
- Positive Samples: Jurkat, human plasma
- Cellular Location: Cell membrane, Single-pass membrane protein
Immunogen sequence:
QSGPLPKPSL QALPSSLVPL EKPVTLRCQG PPGVDLYRLE KLSSSRYQDQ AVLFIPAMKR SLAGRYRCSY QNGSLWSLPS DQLELVATGV FAKPSLSAQP GPAVSSGGDV TLQCQTRYGF DQFALYKEGD PAPYKNPERW YRASFPIITV TAAHSGTYRC YSFSSRDPYL WSAPSDPLEL VVTGTSVTPS RLPTEPPSPV AEFSEATAEL TVSFTNEVFT TETSRSITAS PKESDSPAGP ARQYYTK
Target Information
Glycoprotein VI (GP6) is a 58-kDa platelet membrane glycoprotein crucial for collagen-induced platelet activation and aggregation. Upon vascular injury, exposure of the subendothelial matrix to blood flow leads to platelet deposition. Collagen fibers (types I, III, and VI) are the main thrombogenic components. Platelet interaction with collagen occurs in two steps:
- Initial adhesion to collagen
- Activation leading to secretion, recruitment, and aggregation
This process forms a platelet plug that limits blood loss. However, collagen exposure after atherosclerotic plaque rupture can trigger thrombus formation associated with myocardial infarction or stroke.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.