Thermo Fisher Scientific LRRK2 Polyclonal Antibody
LRRK2 단백질을 인식하는 토끼 폴리클로날 항체로, 파킨슨병 관련 연구에 적합합니다. Western blot에 사용 가능하며, 마우스 시료에서 높은 반응성을 보입니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse LRRK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792898 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%).
- Positive Control: mouse brain, mouse cerebellum, rat brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson’s disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankyrin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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