
Thermo Fisher Scientific GLI1 Monoclonal Antibody (UMAB170), UltraMAB
GLI1 단백질을 표적하는 Thermo Fisher Scientific의 UMAB170 단클론 항체로, Western blot, IHC, ICC/IF, ChIP 등 다양한 응용에 적합합니다. 인간 시료 반응성이 있으며, 고순도 액상 형태로 안정적인 신호 검출을 제공합니다.
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Thermo Fisher Scientific GLI1 Monoclonal Antibody (UMAB170), UltraMAB
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC(P)): 1:100–1:200
- Immunocytochemistry (ICC/IF): 1:100–1:200
- ChIP assay (ChIP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB170 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–410 of human GLI1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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