Thermo Fisher Scientific MUC4 (Mucin 4/Gastric Mucin) Monoclonal Antibody (MUC4/3105)
인체 MUC4 단백질을 인식하는 마우스 단클론 항체로, 면역조직화학(IHC) 및 펩타이드 배열 분석에 적합합니다. 암 및 점막 관련 질환 연구용으로 사용되며, Protein A/G로 정제된 액상 형태의 항체입니다. 연구용 전용 제품입니다.
- 카탈로그번호
- 4585-MSM5-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MUC4 (Mucin 4/Gastric Mucin) Monoclonal Antibody (MUC4/3105)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MUC4/3105 |
| Immunogen | Recombinant fragment (around aa 1730–1864) of human MUC4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nearly all mucosal surfaces are protected by mucin transmembrane glycoproteins, from bronchioles to corneas to reproductive tracts.
Mucin 4 (MUC4) is membrane-bound and plays an important role in protection and lubrication.
MUC4 expression is aberrant in various carcinomas and sarcomas, including fibromyoxoid sarcoma and pancreatic adenocarcinoma.
Immunohistochemical staining for MUC4 has been discussed as a potential biomarker for detection of these cancers.
MUC4 abnormalities are notably associated with certain Asian diseases, such as Taiwanese infertility, endometriosis, and gallstone formation in Chinese men.
Given its critical role in mucosal surface protection, MUC4 dysfunction has been implicated in metastatic cancer invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.