Thermo Fisher Scientific PPP2R5D Monoclonal Antibody (OTI3B3), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Zinc-finger proteins contain DNA-binding domains and perform various functions related to transcriptional activation or repression.
ZNF265 (also known as ZRANB2, ZIS, ZIS1, or ZIS2) is a 330 amino acid nuclear protein belonging to the ZRANB2 family.
It acts as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts and may interfere with constitutive 5'-splice selection.
ZNF265 contains two RanBP2-type zinc fingers that mediate RNA-binding activity.
Two isoforms (ZIS-1 and ZIS-2) are expressed due to alternative splicing, and ZIS-2 may be phosphorylated by ATM or ATR upon DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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