Thermo Fisher Scientific ADAMTS1 Polyclonal Antibody
인간 ADAMTS1 단백질에 특이적인 염소 유래 폴리클로날 항체로, WB, IHC, IP 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 보존제가 없는 동결건조 형태. 연구용으로만 사용.
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- PA548024
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human ADAMTS1 (Leu50–Arg252) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576700 |
Product Specific Information
In direct ELISAs, less than 5% cross-reactivity with mature recombinant human ADAMTS1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The encoded protein contains two disintegrin loops and three C-terminal TS motifs and exhibits anti-angiogenic activity.
Expression of this gene may be associated with inflammatory processes and cancer cachexia. It is likely essential for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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