Thermo Fisher Scientific IFNAR1 Recombinant Rabbit Monoclonal Antibody (1G10)
IFNAR1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, Flow cytometry에 적합합니다. 높은 특이성과 일관된 로트 간 품질을 제공하며, 인간, 마우스, 랫트 시료에 반응합니다. 단백질 A로 정제된 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1G10 |
| Immunogen | Recombinant IFNAR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717288 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
Interferons are therapeutic agents with anti-tumor and antiviral properties and immunomodulatory effects (Biron, 2001; Kirkwood, 2002). These cytokines act by binding to the Type I Interferon Receptor (IFNAR1).
Down-regulation of IFNAR1 influences the magnitude and duration of cytokine signaling, potentially regulated by phosphorylation of Serine 535 and 539 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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