Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI2B6), TrueMAB
NR0B2 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합. 인간 시료에 반응하며, 무보존제 동결건조 형태로 제공. 재구성 후 약 1 mg/mL 농도로 사용 가능. 핵 호르몬 수용체 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Full length human recombinant protein of human NR0B2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR0B2 protein is an orphan nuclear receptor containing a ligand-binding domain but lacking a conventional DNA-binding domain. It belongs to the nuclear hormone receptor family, which includes transcription factors regulated by small hydrophobic hormones.
NR0B2 interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. It represses nuclear hormone receptor-mediated transactivation through competition with coactivators and direct transcriptional repression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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