Thermo Fisher Scientific IL24 Monoclonal Antibody (303308)
마우스 IL-24를 인식하는 Rat IgG2a 형 단클론 항체로 Western blot 및 Immunocytochemistry에 적합함. 인간 IL-24와 교차반응 없음. Lyophilized 형태로 제공되며, PBS + 5% trehalose 버퍼에 재구성 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 303308 |
| Immunogen | E. coli-derived recombinant mouse IL-24 (Arg27–His181) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606278 |
Product Specific Information
- No cross-reactivity with recombinant human IL-24 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein homologous to the IL-10 cytokine family. Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds to heterodimeric receptors IL-22R1/IL-20R2 and IL-20R1/IL-20R2, activating JAK/STAT signaling pathways. Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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