Thermo Fisher Scientific ZWINT-1 Polyclonal Antibody
Human ZWINT-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, IP에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며 4°C에서 보관. 세포 고정 및 투과화 조건에 최적화된 연구용 항체.
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Thermo Fisher Scientific ZWINT-1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and the C-terminus (residue 277) of Human ZW10 Interactor-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For ICC, formaldehyde fixation is recommended
- Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells
Target Information
This gene encodes a protein involved in kinetochore function, though its exact role is not fully understood. It interacts with ZW10, potentially regulating the association between ZW10 and kinetochores. The protein localizes to prophase kinetochores before ZW10 and remains detectable until late anaphase. It is uniformly distributed in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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