Thermo Fisher Scientific Phospho-Cardiac Troponin I (Ser150) Polyclonal Antibody
Cardiac Troponin I Ser150 인산화형을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합하며 Human, Mouse, Rat 반응성을 가집니다. 고순도 Affinity chromatography 정제 제품으로 약 0.25 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser150 of mouse TNNI3 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | ~0.25 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 50% glycerol, 0.1mg/mL BSA |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552720 |
Product Specific Information
- This antibody is predicted to react with human and non-human primate based on 100% sequence homology.
- Contains enough material to conduct 10 mini-Western blots.
Target Information
Cardiac Troponin I (TnI) is an integral inhibitory protein in cardiac muscle, forming a complex with troponin C (TnC) and troponin T (TnT). It binds to actin within muscle thin filaments and regulates contraction through calcium-mediated conformational changes.
Measurement of blood TnI and TnT levels serves as a diagnostic indicator of cardiac muscle damage, differentiating angina from myocardial infarction.
Cardiac Troponin I also inhibits angiogenesis in vivo and in vitro. Mutations in its gene are associated with familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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