Thermo Fisher Scientific Phospho-SQSTM1 (Ser28) Polyclonal Antibody
Human SQSTM1 단백질의 Ser28 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 비인간 영장류에도 반응 예측. 고순도 친화 크로마토그래피 정제, 10회 미니 웨스턴 블롯 수행 가능.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser28 of human SQSTM1 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | ~0.25 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 50% glycerol, 0.1mg/mL BSA |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552719 |
Product Specific Information
- Predicted to react with non-human primate based on 100% sequence homology.
- Contains enough material to conduct 10 mini-Western blots.
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway.
The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals.
Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.
Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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