Thermo Fisher Scientific TAS2R38 Polyclonal Antibody
TAS2R38 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 마우스 반응성, Rabbit/Ig 기원, 동결건조 형태이며 연구용으로만 사용됩니다.
- 카탈로그번호
- OST00395W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:1,000
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse TAS2R38 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TAS2R38.
Target Information
Receptor that may play a role in the perception of bitterness and is gustducin-linked.
May play a role in sensing the chemical composition of the gastrointestinal content.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Variations in TAS2R38 are associated with the ability to taste phenylthiocarbamide (PTC tasting); also called thiourea tasting.
The ability to taste the substance PTC and related substances is genetically controlled.
Genetic studies have demonstrated complex inheritance for this trait.
For some people (and some chimpanzees also), PTC tastes very bitter; for others, it is tasteless.
Substantial variation in taste sensitivity exists in humans.
Five haplotypes arising from three coding SNPs in the TAS2R38 gene are associated with distinct phenotypes of PTC taste sensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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