Thermo Fisher Scientific Epigen Polyclonal Antibody
인간 Epigen 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보관됩니다. Epigen의 세포 성장 및 신호전달 연구에 활용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Epigen. Recombinant protein control fragment (Product #RP-90531) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663739 |
Product Specific Information
Immunogen sequence:
ALTEEAAVTVT PPITAQQGNW TVNKTEADNI EGPIALKFSH LCLEDHNSYC INGACAFHHE LEKAICRCFT GYTGERCEHL TLTSYAVDSYE
- Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 80%
Target Information
Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It promotes the growth of epithelial cells and may stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Epigen is expressed in several tissues, including testis, liver, and heart, and in certain tumor cells. It is mitogenic for fibroblasts and epithelial cells.
Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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