Thermo Fisher Scientific SERPINA3 Polyclonal Antibody
Human SERPINA3 단백질을 인식하는 Goat Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. 0.5 mg/mL 농도의 액상 형태이며, TBS(pH 7.3, 0.5% BSA) 버퍼에 보관. 알츠하이머병 관련 단백질 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DPQDTHQSRFYLSKK (aa 222–236) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933774 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer’s disease (AD) and in normal aged human and monkey brain.
Regulation of serine proteases and their inhibitors plays an important role in neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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