Thermo Fisher Scientific 5HT2A R Polyclonal Antibody
Rabbit polyclonal antibody targeting human 5HT2A receptor for WB and IHC applications. Lyophilized form with whole serum buffer, no preservative. Suitable for research use in serotonin receptor studies related to cardiovascular and neurological functions.
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Thermo Fisher Scientific 5HT2A R Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human 5HT2A receptor conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: 5HT2A receptor.
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility. It mediates its effects through G protein-coupled receptors known as 5-HT or SR receptors.
The SR-2 receptor family includes SR-2A, SR-2B, and SR-2C subtypes, which activate phospholipase C and release intracellular calcium in response to serotonin.
- SR-2A: Involved in tracheal smooth muscle contraction, bronchoconstriction, aldosterone production, and psychiatric disorders such as depression and schizophrenia.
- SR-2B: Expressed in cardiovascular tissues, gut, and brain; important in cardiac pathology.
- SR-2C: Mediates effects of atypical antipsychotic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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