Thermo Fisher Scientific GCDH Polyclonal Antibody
Thermo Fisher Scientific의 GCDH Polyclonal Antibody는 인간, 생쥐, 랫드 시료에 반응하며 WB, IHC, ELISA에 적합합니다. 미토콘드리아 매트릭스 내 GCDH 단백질 검출용으로 고순도 친화 크로마토그래피 정제 제품입니다.
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Thermo Fisher Scientific GCDH Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 149–438 of human GCDH (NP_0001501) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2808984 |
Product Specific Information
- Immunogen sequence:
MHPIYAYGSE EQRQKYLPQL AKGELLGCFG LTEPNSGSDP SSMETRAHYN SSNKSYTLNG TKTWITNSPM ADLFVVWARC EDGCIRGFLL EKGMRGLSAP RIQGKFSLRA SATGMIIMDG VEVPEENVLP GASSLGGPFG CLNNARYGIA WGVLGASEFC LHTARQYALD RMQFGVPLAR NQLIQKKLAD MLTEITLGLH ACLQLGRLKD QDKAAPEMVS LLKRNNCGKA LDIARQARDM LGGNGISDEY HVIRHAMNLE AVNTYEGTHD IHALILGRAI TGIQAFTASK - Positive Samples: HL-60, LO2, MCF-7, BT-474, Mouse liver, Rat liver, Rat kidney
- Cellular Location: Mitochondrion matrix
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO₂ in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kDa subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-97182_GCDH_Q92947-1_Rabbit.svg)
(이미지: PA5-97182_GCDH_Q92947-1_Rabbit_PDP.jpeg)
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