Thermo Fisher Scientific OX40/CD134 Recombinant Rabbit Monoclonal Antibody (BLR042F)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100 - 1:500

-

Immunocytochemistry (ICC/IF)

1:100 - 1:500

-

Flow Cytometry (Flow)

4 µL per 1 x 10^6 cells

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

BLR042F

Immunogen

Recombinant protein representing the extracellular domain of human OX40/CD134 (residues 29-216). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OX40 (CD134),uniProtId:P43489-1,ncbiNodeId:9606,antigenRange:29-216,antigenLength:277,antigenImageFileName:A700-042_OX40_CD134_P43489-1_Rabbit.svg,antigenImageFileNamePDP:A700-042_OX40_CD134_P43489-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

50 µg/mL

Purification

purified

Storage buffer

BBS, pH 7.8 to 8.6, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

Target Information

OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.