Thermo Fisher Scientific Human EIF2AK1 (HRI), GST Tag Recombinant Protein
인간 EIF2AK1(HRI) 단백질을 GST 태그로 재조합한 Thermo Fisher Scientific 제품. Baculovirus 발현 시스템 사용, 정제된 액상 형태. 단백질 합성 조절 연구용으로 적합하며, -80°C 보관 시 안정적. 진단용이 아닌 연구용으로만 사용.
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Thermo Fisher Scientific Human EIF2AK1 (HRI), GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Baculovirus |
| Amino Acid Sequence | Full length |
| Tag | GST-tag |
| Molecular Weight | 98.6 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
- For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
- Never store kinase diluted.
- Proper storage at -80°C ensures stability for 6 months from date of purchase.
- Protein Form: Full Length
Target Information
EIF2AK1 (HRI) is one of four kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to decreased protein synthesis. EIF2AK1 signaling is initiated by low levels of heme. The HRI gene is localized to 7p22, where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands, with kinase activity induced by low heme and inhibited by heme presence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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