Thermo Fisher Scientific Human EIF2AK1 (HRI), GST Tag Recombinant Protein

Thermo Fisher Scientific Human EIF2AK1 (HRI), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: -

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Unless noted below, aliquots of the 5 µg, 10 µg, and 20 µg sizes of kinase are not recommended, as materials can be used directly from the original packaging until exhausted.
For larger sizes, reduce freeze/thaw cycles by preparing aliquots (below 20 µL aliquots are not recommended).
Do not store a diluted kinase.
If properly stored at -80°C, this product is guaranteed for 6 months from the date of purchase.

Protein Form: Full Length

Target Information

EIF2AK1 (HRI) is one of four kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to environmental stresses, leading to decreased protein synthesis.
Signaling by EIF2AK1 is initiated under low heme levels.
The HRI gene is localized to chromosome 7p22, where its 3' end slightly overlaps with the 3' end of the JTV1 gene.
The two genes are transcribed from opposite strands.
Kinase activity is induced by low heme levels and inhibited by the presence of heme.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.