Thermo Fisher Scientific DNMT2 Polyclonal Antibody
DNMT2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼(40% glycerol 포함) 상태로 제공되며, 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNMT2. Recombinant protein control fragment (Product #RP-103678) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640731 |
Product Specific Information
Immunogen sequence:
KIESVHPQKY AMDVENKIQE KNVEPNISFD GSIQCSGKDA ILFKLETAEE IHRKNQQDSD LSVKMLKDFL EDDTDVNQYL LPPKSLLRYA L
Sequence identity:
- Mouse: 62%
- Rat: 60%
Target Information
CpG methylation is an epigenetic modification important for embryonic development, imprinting, and X-chromosome inactivation. DNA methylation is required for mammalian development. This gene encodes a protein similar to DNA methyltransferases, but lacking methyltransferase activity. The protein binds DNA strongly and may mark specific genomic sequences. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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