Thermo Fisher Scientific HCCS Monoclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 5–10 µg/mL

Product Specifications

Product Specific Information

MA1-26475 will not react with bovine, guinea pig, equine, or porcine.

Target Information

CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein that belongs to the cytochrome c-type heme lyase family.
Containing two HRM (heme regulatory motif) repeats, HCCS participates in the covalent linkage of a heme group to an apoprotein of cytochrome c.
The gene encoding HCCS maps to the human X chromosome.
Defects in this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS).
MCOPS7 is an X-linked male-lethal disorder that results in eye deformation, unilateral or bilateral microphthalmia, linear skin defects in affected females, and in utero lethality for males.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.