
Thermo Fisher Scientific HCCS Monoclonal Antibody
HCCS 단백질을 표적하는 Thermo Fisher Scientific의 Mouse IgG1 단클론 항체. Western blot에 최적화된 5–10 µg/mL 사용 농도. 인간 심장에서 정제된 cytochrome c로 면역화됨. 장기 보관은 -20°C에서 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- MA126475
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Cytochrome c purified from human heart |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_794501 |
Product Specific Information
MA1-26475 will not react with bovine, guinea pig, equine, or porcine.
Target Information
CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein that belongs to the cytochrome c-type heme lyase family.
Containing two HRM (heme regulatory motif) repeats, HCCS participates in the covalent linkage of a heme group to an apoprotein of cytochrome c.
The gene encoding HCCS maps to the human X chromosome.
Defects in this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS).
MCOPS7 is an X-linked male-lethal disorder that results in eye deformation, unilateral or bilateral microphthalmia, linear skin defects in affected females, and in utero lethality for males.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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