Thermo Fisher Scientific ITIH4 Polyclonal Antibody
Human ITIH4 단백질을 인식하는 goat polyclonal antibody로, WB 및 IHC(P) 검증 완료. 두 가지 isoform 모두 인식하며, 0.5 mg/mL 농도의 액상 형태로 제공. 연구용으로 세포 외 기질 관련 단백질 분석에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.03–0.1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SDDGRRTLRVQGND |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933390 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_002209.2; NP_001159921.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The inter-alpha-trypsin inhibitor (ITI, I-alpha-I) family represents protein–glycosaminoglycoprotein (PGP) complexes found constitutively in plasma at high concentrations. These complexes consist of three heavy chains and a common light chain, bikunin proteoglycan. Bikunin contains two Kunitz-type protease inhibitor domains that inhibit trypsin, leukocyte elastase, and plasmin.
The heavy chains interact with hyaluronic acid, contributing to extracellular matrix stability. The ITI protein family is thought to play a key role in extracellular matrix biology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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