Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (IRDN/805)
베타세포 및 인슐린종 표지용 단클론 항체로 다양한 종에서 반응. 파라핀 및 PFA 고정 조직 IHC에 사용 가능. Recombinant INS 항원으로 제작된 Mouse IgG1 항체. 연구용 전용 제품으로 높은 특이성과 재현성 제공.
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Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (IRDN/805)
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: Assay-dependent
- Immunohistochemistry (PFA fixed) [IHC (PFA)]: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Pig, Rabbit |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IRDN/805 |
| Immunogen | Recombinant INS protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Rat
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide derived from proinsulin, which is cleaved post-translationally into two chains (peptide A and peptide B) linked by disulfide bonds and one molecule of C-peptide.
Insulin deficiency leads to diabetes mellitus, a major cause of morbidity and mortality. Insulin is also detected in tumors of beta-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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