Thermo Fisher Scientific MCM2 Monoclonal Antibody (OTI1C7), TrueMAB
인간 MCM2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 동결건조 형태로 제공되며, 1 mg/mL 농도, PBS/trehalose 버퍼에 저장됩니다. DNA 복제 조절 및 세포주기 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C7 |
| Immunogen | Full length human recombinant protein of human MCM2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
To use this carrier-free antibody for conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication.
MCM2 (also known as CDCL1, mitotin, and BM28) is a nuclear protein crucial for the cell cycle, particularly at the onset of DNA replication and cell division.
It belongs to the family of early S-phase proteins and is mapped to chromosome 3q21.
CDCL1 has been considered a candidate oncogene associated with chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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