Thermo Fisher Scientific AMPK beta-1 Polyclonal Antibody
AMPK beta-1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합. 인간, 마우스, 원숭이, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PRKAB1 (Accession Q9Y478), corresponding to amino acid residues K156–L206 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899484 |
Product Specific Information
Antibody detects endogenous levels of total AMPK beta 1.
Target Information
AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It acts as an important energy-sensing enzyme that monitors cellular energy status. Upon metabolic stress, AMPK is activated and phosphorylates key enzymes such as acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), regulating fatty acid and cholesterol biosynthesis. The beta 1 subunit may positively regulate AMPK activity and serve as an adaptor molecule mediating complex association. Myristoylation and phosphorylation of this subunit influence enzyme activity and localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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