Thermo Fisher Scientific Ku70 Monoclonal Antibody (2F7F5)
Ku70 단백질을 인식하는 Mouse IgG1 단클론 항체로, 인간 시료에 반응합니다. WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합합니다. 정제된 XRCC6 단백질 조각을 면역원으로 사용하였으며, 단백질 G로 정제된 액상 형태입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F7F5 |
| Immunogen | Purified recombinant fragment of human XRCC6 (aa: 6–214) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898574 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase and may be involved in repair of nonhomologous DNA ends, such as those required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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