Thermo Fisher Scientific Diazepam Binding Inhibitor Polyclonal Antibody
Human DBI 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DBI. Recombinant protein control fragment (Product # RP-103098) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791218 |
Product Specific Information
Immunogen sequence:
MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGD
Target Information
This gene encodes diazepam binding inhibitor, a protein regulated by hormones and involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors in brain synapses.
The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that form the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters.
Diazepam binding inhibitor also mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin, and acts as a mediator in corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes located on chromosomes 6, 8, and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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